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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCT
All Species:
7.88
Human Site:
Y1903
Identified Species:
19.26
UniProt:
P09848
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09848
NP_002290.2
1927
218573
Y1903
C
G
L
A
F
L
S
Y
K
Y
C
K
R
S
K
Chimpanzee
Pan troglodytes
XP_522655
1012
116155
L989
L
L
A
F
I
A
F
L
F
F
A
F
I
I
S
Rhesus Macaque
Macaca mulatta
XP_001096426
1928
218172
Y1904
C
G
L
A
F
L
S
Y
K
Y
C
K
R
S
K
Dog
Lupus familis
XP_541018
1371
156201
K1348
C
V
A
F
L
S
Y
K
Y
C
K
H
S
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35082
1014
116407
L991
L
L
V
F
I
S
F
L
V
F
T
F
I
I
S
Rat
Rattus norvegicus
Q02401
1928
217249
Y1904
C
S
L
A
F
L
T
Y
N
T
G
R
R
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515349
1797
200802
V1774
P
T
V
C
N
I
W
V
L
V
T
I
L
P
L
Chicken
Gallus gallus
NP_001104816
1935
219845
L1912
I
G
A
L
G
L
A
L
I
S
Y
K
Y
G
T
Frog
Xenopus laevis
NP_001106299
607
69234
A584
E
F
A
F
L
I
A
A
V
L
G
I
V
L
L
Zebra Danio
Brachydanio rerio
XP_001336765
1897
215948
F1872
V
T
V
I
F
L
V
F
G
L
V
R
T
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.1
95.9
62.9
N.A.
23
78
N.A.
55.4
63.6
22.2
53.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
34.9
97.8
66.9
N.A.
35
87.1
N.A.
65.9
77.9
27
69.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
6.6
N.A.
0
60
N.A.
0
20
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
13.3
N.A.
13.3
73.3
N.A.
13.3
26.6
13.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
40
30
0
10
20
10
0
0
10
0
0
0
0
% A
% Cys:
40
0
0
10
0
0
0
0
0
10
20
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
40
40
0
20
10
10
20
0
20
0
0
0
% F
% Gly:
0
30
0
0
10
0
0
0
10
0
20
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
10
20
20
0
0
10
0
0
20
20
20
0
% I
% Lys:
0
0
0
0
0
0
0
10
20
0
10
30
0
10
40
% K
% Leu:
20
20
30
10
20
50
0
30
10
20
0
0
10
10
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
20
30
0
0
% R
% Ser:
0
10
0
0
0
20
20
0
0
10
0
0
10
40
20
% S
% Thr:
0
20
0
0
0
0
10
0
0
10
20
0
10
0
10
% T
% Val:
10
10
30
0
0
0
10
10
20
10
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
30
10
20
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _